1481Centuries: 14th century - 15th century - 16th century
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- Anjou was reverted to the French crown.
- Change of King of Denmark and Norway from Christian I (1448-1481) to John (1481-1513)
- Change of emperor of the Ottoman Empire from Mehmed II (the Conqueror) (1451-1481) to Beyazid II (1481-1512)
- Change of Patriarch Maximus III (1476-1481) to Symeon I (1466, 1471-1474, 1481-1486)
- Fire destroyed the roof and the spires of the Cathedral of Notre Dame at Reims
- Tizoc, the Aztec ruler of the city of Tenochtitlan, rose to power
- Famous Aztec Calendar Stone or "Sun Stone" carved
- The Spanish Inquisition began (until 1820)
- Treaty of Tordesillas - The papal Bull Aeterni regis had granted all land south of the Canaries to Portugal.